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Title:  Sr Scientist, Purification - Advanced Therapies

Requisition ID:  58422
Date:  Nov 18, 2022
Location: 

Exton, Pennsylvania, US

Department:  R&D
Description: 

 

 

Working at West means having an opportunity to work by the side of our patients and customers, our global team members and the communities in which we operate – which all help contribute to a Healthier World.

 

At West, we are by the side of patients. The work we do impacts patients’ lives each and every day – our products are a critical part of healthcare delivery and we are proud of the role we play to improve patient health. We work by the side of our team members. We come together as one global team to deliver for our customers and help them address their challenges. We are a diverse, close-knit community of professionals, where everyone has a voice and opportunity to learn and grow through mutual trust and respect. With a 95 year plus history, we have a track record for success, which includes reported sales of $2.14B in 2020. We serve by the side of our community. Giving back is in our DNA—our team members across more than 50 sites globally are involved with hundreds of charities that have special meaning to them through our West Without Borders team member-led giving program.

 

Job Summary:

The Advanced Therapies team within West is responsible for driving the future of the company by developing innovative products designed to improve patient lives. This role is tasked with working on big ‘R’ research on behalf of the rest of the R&D organization and will keenly focus on technology fields that are adjacent and transformational to West’s core products.

The team is expanding our research in the field of life sciences and seeking a candidate who can join our multidisciplinary team. Advanced Cell Therapies are growth engine that will unlock a vast array of future applications from addressing unmet medical needs, controlled release drug delivery, encapsulating cell therapies, improving the lifespan of biosensors to future applications in the emerging fields of bioprinting and implantable systems.

We are seeking a highly collaborative candidate who is knowledgeable about vectors for the delivery of in vivo and ex vivo gene therapies, non-viral delivery platforms such as mRNA and an expert on protein purification. Successful candidate will interface internally with our scientists and engineers working on advanced therapies, nanomaterials, biosensors, and drug delivery programs. The role will also be expected to build links externally with researchers, and biotech companies, leading to new technologies being brought to the attention of the West R&D Leadership.

In collaborating across this wide array of stakeholders, the candidate would use the insights gained to design and execute experimental studies. These studies will inform West’s development decisions for research and investment into highly disruptive future technologies that may change the way novel therapies are delivered.

Suitable candidates are expected to bring a depth of expertise, knowledge of current developments in both research and industry, and will make a significant contribution to the R&D Team and the future of West. 

Essential Duties and Responsibilities:

  • Design, develop and execute experiments for purification of virus particles from process-and product - related impurities including host cell material, plasmid DNA, and empty capsids.
  • Develop applications for use in non-viral delivery platforms such as mRNA
  • Support scientific or engineering expertise in cell and gene therapy space toward the design and development of cost-effective purification solutions.
  • Evaluate project proposals for applying different technologies and ideas that are used in development of advanced therapies.
  • Manage and contribute to complex research projects across several technologies and a variety of project formats, from short-term student internships, through to feasibility projects and long-term collaborations.
  • Collaborate and gain commitment with stakeholders internally within West as well as externally with research partners (postdocs, professors and clinicians) as needed to achieve project objectives.
  • Analyze and evaluate experimental results to make well-reasoned strategic recommendations that are to be disseminated internally to inform future research and development decisions at West.
  • Actively seek out new and emerging technologies and therapies, track publications, identify and highlight active academics and keep our organization informed of research and industry developments.
  • Provide subject matter expertise across the organization in the field of applied research in advanced therapeutic cell technologies.
  • Capture project outputs in appropriate format including: technical reports, presentation slides, research posters, invention disclosures or as project requires.
  • Travel to select targeted scientific and research conferences to learn and present out research findings with intention of increasing West scientific reputation in novel fields.

Basic Qualifications

  • Education: Masters in life sciences, chemical engineering, bioengineering or equivalent scientific discipline.
  • Experience: 5-8 years of experience, can include time spent either in industry or graduate school.
  • Hands-on experience of protein purification and/or advanced therapies purification process. Experience with development of methods for various chromatography techniques.
  • Demonstrated ability to lead complex research projects, can either be shown in relevant industry projects or via strong collaborative postgraduate research.
  • Strong interpersonal skills to generate, maintain and grow research relationships and gain commitment from all internal and external stakeholders across research projects.
  • Excellent written and verbal communication and ability to articulately disseminate scientific research to a variety of different audiences, from expert through to non-technical.

Preferred Knowledge, Skills and Abilities

  • Education: PhD in life sciences, chemical engineering, bioengineering or equivalent scientific discipline.
  • Scientific publication track record and/or conference proceedings in a chosen field of expertise.
  • Existing established North American network of academic and/or industry collaborators.
  • Understanding of regulated manufacturing environments, i.e. aseptic and GMP production.
  • Working knowledge related to manufacturing or process development experience in biotech industry
  • Maintain the ability to work well with others in a variety of situations.
  • Able to multi-task, work under time constraints, problem solve, and prioritize.

Travel Requirements

  • Must be able to travel domestically or internationally up to 10% of the time.

 

 

 

 

 

 

West is an equal opportunity employer and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sex, gender identity, sexual orientation, age, marital status, veteran status, or disability status.  If you have a special need that requires accommodation in order to apply to West, please send an email to Apply.Accommodation@westpharma.com.  Where permitted by law, an offer of employment with West Pharmaceutical Services, or any of its subsidiary or affiliate companies, is contingent upon the satisfactory completion of background screening and/or a pre-employment drug screening.

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