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Title:  Senior Scientist - Immunoassay Development, POC Biosensor

Requisition ID:  48499
Date:  Sep 18, 2022
Location: 

Exton, Pennsylvania, US

Department:  R&D
Description: 

 

 

Working at West means having an opportunity to work by the side of our patients and customers, our global team members and the communities in which we operate – which all help contribute to a Healthier World.

 

At West, we are by the side of patients. The work we do impacts patients’ lives each and every day – our products are a critical part of healthcare delivery and we are proud of the role we play to improve patient health. We work by the side of our team members. We come together as one global team to deliver for our customers and help them address their challenges. We are a diverse, close-knit community of professionals, where everyone has a voice and opportunity to learn and grow through mutual trust and respect. With a 95 year plus history, we have a track record for success, which includes reported sales of $2.14B in 2020. We serve by the side of our community. Giving back is in our DNA—our team members across more than 50 sites globally are involved with hundreds of charities that have special meaning to them through our West Without Borders team member-led giving program.

 

Job Summary:

The Applied Research & Technology Scouting (AR&TS) team within West is responsible for driving the future of the company by identifying and developing innovative products designed to improve patient lives.  This objective will be accomplished through a mix of internal organic research and external inorganic collaboration.  The inorganic effort will span early-stage academic research to more established technologies in the private sector.  The inorganic effort will seed the organic efforts. The scope encompasses technology fields that are adjacent to and transformational to West’s core products.

The role will work within the recently established Diagnostic Research & Detection Technology team to identify and evaluate technologies and concepts in a broadly defined Biosensor space.  The team’s output will feed the development of new products and serve new markets. The timeline for realization of the products is within a 5-year time horizon. Internal to West this team will collaborate with teams focused on drug delivery and novel therapies. External to West the team will be interfacing with researchers from academic institutions translating potential value-adding technologies, through feasibility and into reality. Projects will focus on technology validation and integration.  This will require the planning and performing of experiments, designing test equipment and prototypes, and integrating different principles of optical, mechanical, and electronic engineering.

Amongst the many research avenues of interest to West is the exploration of advanced biometric sensor technologies, and their potential integration into next generation drug delivery devices.  Suitable candidates will be expected to bring a depth of expertise, knowledge of current developments in both research and industry, and will make a significant contribution to the I&T Team and the future of West.

Essential Duties and Responsibilities:

  • Provide subject matter expertise across the immunoassay and related biomarker technology landscape.
  • Design and develop immune based assays including antibody characterization and validation, sandwich assay assembly, western protein analysis, and immunoprecipitation for other downstream protein analysis.
  • Perform immune assay characterization for LOQ, LLOQ, specificity, reproducibility, matrix effects, dynamic range, robustness, accuracy, recovery, precision, repeatability (inter-assay variation, reproducibility), linearity etc.
  • Design experimental plans and project proposals to evaluate different technologies and test hypotheses.
  • Evaluate and solve complex technical challenges that arise on both internal and external projects. Gather and provide new perspectives and arrive at solutions based on pooling multiple sources of information.
  • Solve problems using own judgement and persevere when setbacks threaten project goals.
  • Capture project outputs in appropriate format including technical reports, presentation slides, research posters, invention disclosures or as project permits.
  • Support technology evaluations and assessment for M&A opportunities.
  • Participate as a team member on various projects within the group and perform other duties as assigned based on business needs.

Basic Qualifications:

  • Education:  BS ( 8 years), Master’s (5-8 years) or PhD (3-5 year) degree in biochemistry, microbiology, immunology, molecular biology, or closely related scientific disciplines is required
  • Possess strong expertise in assay development and bio-analytical methods
  • Background working in medical device or similarly regulated industry.
  • Demonstrated ability to support complex research projects either through relevant industry projects or via strong collaborative research.
  • Willingness to learn and to independently explore new fields of research, understand nascent technologies.
  • Excellent written and verbal communication and ability to articulately disseminate scientific research to a variety of different audiences, from biomedical, mechanical, electronic engineering or equivalent expert through to non-technical.

 

Preferred Knowledge, Skills and Abilities:

  • Fundamental understanding of protein biochemistry and bioconjugation chemistry.
  • Hands-on experience with ligand binding immunoassays is required.
  • Experience with bioanalytical assay development and validation, and common bioanalytical techniques such as spectroscopy, gel electrophoresis, etc.
  • Hands-on experience with different sample preparation procedures such as protein precipitation, liquid-liquid extraction, solid-phase extraction and immunocapture approaches.
  • Skilled at method development and validation.
  • Expertise in designing and developing biochemical assays used to detect biomarkers in biological samples.
  • Experience with PCR, and cell-based bioassay is a plus.
  • Able to be aware of all relevant SOPs as per Company policy as they are related to the position covered by this Job Description

 

Travel Requirements:

  • Must be able to travel domestically or internationally up to 15% of the time

 

Physical & Mental Requirements:

  • Must maintain the ability to work well with others in a variety of situations.
  • Must be able to multi-task, work under time constraints, problem solve, and prioritize.

 

 

 

 

 

 

West is an equal opportunity employer and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sex, gender identity, sexual orientation, age, marital status, veteran status, or disability status.  If you have a special need that requires accommodation in order to apply to West, please send an email to Apply.Accommodation@westpharma.com.  Where permitted by law, an offer of employment with West Pharmaceutical Services, or any of its subsidiary or affiliate companies, is contingent upon the satisfactory completion of background screening and/or a pre-employment drug screening.

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